Spain's Foreign Minister Alfonso Dastis met on Wednesday with Cuban President Raul Castro in Havana during an official visit to the island.
Cuba's state daily Granma reported Castro and Dastis had discussed bilateral relations saying both sides were satisfied with developing relations which they both hoped would continue to strengthen.
Dastis is seeking to strengthen ties after the 2016 signing of the first Political Dialogue and Cooperation Agreement between Cuba and the European Union.
Spain is the country with the most joint ventures on the island and is Cuba's first trading partner in Europe. Globally it is third after China and Venezuela, respectively.
Also at the meeting were the Spanish ambassador to Cuba, Juan Jose Buitrago de Benito as well as Dastis' Cuban counterpart, Bruno Rodriguez.
Wednesday's meeting came has Hurricane Irma was thrashing its way through the northern Caribbean towards Cuba and Florida where it is expected to make landfall later this week.