When fathers exercise, children are healthier, even as adults

Men who want to have children in the near future should consider hitting the gym.

In a new study led by Kristin Stanford, a physiology and cell biology researcher with The Ohio State University College of Medicine at the Wexner Medical Center, paternal exercise had a significant impact on the metabolic health of offspring well into their adulthood.

Laurie Goodyear of the Joslin Diabetes Center and Harvard Medical School co-led the study, published today in the journal Diabetes.

"This work is an important step in learning about metabolic disease and prevention at the cellular level," said Dr. K. Craig Kent, dean of the Ohio State College of Medicine.

Recent studies have linked development of type 2 diabetes and impaired metabolic health to the parents' poor diet, and there is increasing evidence that fathers play an important role in obesity and metabolic programming of their offspring.

Stanford is a member of Ohio State's Diabetes and Metabolism Research Center. Her team investigated how a father's exercise regimen would affect his offspring's metabolic health. Using a mouse model, they fed male mice either a normal diet or a high-fat diet for three weeks. Some mice from each diet group were sedentary and some exercised freely. After three weeks, the mice bred and their offspring ate a normal diet under sedentary conditions for a year.

The researchers report that adult offspring from sires who exercised had improved glucose metabolism, decreased body weight and a decreased fat mass.

"Here's what's really interesting; offspring from the dads fed a high-fat diet fared worse, so they were more glucose intolerant. But exercise negated that effect," Stanford said. "When the dad exercised, even on a high-fat diet, we saw improved metabolic health in their adult offspring."

Stanford's team also found that exercise caused changes in the genetic expression of the father's sperm that suppress poor dietary effects and transfer to the offspring.

"We saw a strong change in their small-RNA profile. Now we want to see exactly which small-RNAs are responsible for these metabolic improvements, where it's happening in the offspring and why," Stanford said.

Previous studies from this group have shown that when mouse mothers exercise, their offspring also have beneficial effects of metabolism.

"Based on both studies, we're now determining if both parents exercising has even greater effects to improve metabolism and overall health of offspring. If translated to humans, this would be hugely important for the health of the next generation," Goodyear said.

The researchers believe the results support the hypothesis that small RNAs could help transmit parental environmental information to the next generation.

"There's potential for this to translate to humans. We know that in adult men obesity impairs testosterone levels, sperm number and motility, and it decreases the number of live births," Stanford said. "If we ask someone who's getting ready to have a child to exercise moderately, even for a month before conception, that could have a strong effect on the health of their sperm and the long-term metabolic health of their children."

Other Ohio State researchers involved in the study were Lisa Baer, Adam Lehnig and Joseph White.

Funding from the National Institutes of Health supported this research.

Ocean Research Challenges under Debate at MarCuba 2018

Havana, Oct 17 (Prensa Latina) Specialists from the Exclusive Economic Zone of the Gulf of Mexico are discussing on Wednesday in Havana the ocean research challenges, as part of the 11th Congress on Marine Sciences, to be run until Friday, October 19.

In order to advance in a common debate on the conservation of marine species throughout the Gulf of Mexico, the delegates to the event took up the motto 'Today's sciences in the interest of future coasts and seas.'

The symposium 'Numerical simulation of weather conditions during extreme events and its effect on sea turtle nesting', by Cuban experts, also provokes an intense scientific interchange today.

Those interested in issues related to climate change met in a panel dedicated to the determination of coral reef areas affected by the dispersion of particles at present and for 2100.

Other issuecs under discussion are related to the actions carried out by the Cuban National Aquarium for the protection of marine ecosystems, among which are the technologies applied to maintain living collections, as well as assess structure, abundance and population of the species in their natural environment.

Opened on Monday with the aim of preserving marine ecosystems, MarCuba 2018 brings together delegates from more than 12 countries in Latin America, Europe and Asia, as well as the United States.

Eating with your eyes: Virtual reality can alter taste

Humans not only relish the sweet, savory and saltiness of foods, but they are influenced by the environment in which they eat. Cornell University food scientists used virtual reality to show how people's perception of real food can be altered by their surroundings, according to research published in the Journal of Food Science.

"When we eat, we perceive not only just the taste and aroma of foods, we get sensory input from our surroundings -- our eyes, ears, even our memories about surroundings," said Robin Dando, associate professor of food science and senior author of the study.

About 50 panelists who used virtual reality headsets as they ate were given three identical samples of blue cheese. The study participants were virtually placed in a standard sensory booth, a pleasant park bench and the Cornell cow barn to see custom-recorded 360-degree videos.

The panelists were unaware that the cheese samples were identical, and rated the pungency of the blue cheese significantly higher in the cow barn setting than in the sensory booth or the virtual park bench.

To control for the pungency results, panelists also rated the saltiness of the three samples -- and researchers found there was no statistical difference among them.

The purpose of this project was to develop an easy-to-implement and affordable method for adapting virtual reality technology for use in food sensory evaluation, said Dando.

Our environs are a critical part of the eating experience, he said. "We consume foods in surroundings that can spill over into our perceptions of the food," said Dando. This kind of testing offers advantages of convenience and flexibility, compared to building physical environments.

"This research validates that virtual reality can be used, as it provides an immersive environment for testing," said Dando. "Visually, virtual reality imparts qualities of the environment itself to the food being consumed -- making this kind of testing cost-efficient."

Gangrene-causing bacteria could treat late-stage cancers – study

While it may be lethal in high doses, a new study suggests that a gangrene-causing bacteria could prove a promising treatment for late-stage cancer tumours that have become immune to existing treatments.

Conducted by doctors at the University of Texas, the ground-breaking study saw late-stage cancer patients’ tumours injected with spores of a modified bacterial strain related to the lethal hospital superbug, clostridium difficile.

The first phase of the study involved 24 patients with solid tumours that had become resistant to existing treatments such as chemotherapy.

Known as Clostridium novyi-NT, the strain thrives in the dense cancerous tissues as it doesn’t need high quantities of oxygen to survive. Healthy tissue meanwhile, is rich in oxygen so the bacteria won’t develop.

Two patients who were given the highest doses developed severe sepsis and “gas gangrene.” But, for the remaining 22 patients, this new type of “bacterial therapy” instead attacked the cancerous tissues causing them to become necrotic and shrink.

“Even after a single injection of this bacterial therapy, we see biological and, in some patients, clinically meaningful activity,” said Dr Filip Janku of the university’s Anderson Cancer Center ahead of the study being presented at the International Cancer Immunotherapy Conference in New York on Sunday.

READ MORE: Cancer mapping tech could help UK doctors stay one step ahead of tumors

In 23 percent of cases, the tumours shrank in size by more than 10 per cent and Janku is confident that even greater shrinkage was possible as the initial treatment caused inflammation of the tumours while they were being attacked.

“Extremely encouraged” by the results of this trial, Janku added that even when the spores did not develop, the presence of the bacteria helped to active dormant immune system cells to also attack the tumour.

While the treatment has yet to be published in a scientific journal or go through the significant process of human testing for safety and long-term trails, Janku believes this “bacteriolytic strategy” could be “clinically meaningful” when used with existing immunotherapies.

More than half of parents of sleep-deprived teens blame electronics

It's no secret that many teenagers stay up late to scroll through social media or catch up with friends on phones.

And 56 percent of parents of teens who have sleep troubles believe this use of electronics is hurting their child's shut-eye.

Forty-three percent of parents report that their teen struggles to fall asleep or wakes up and can't get back to sleep, according to the C.S. Mott Children's Hospital National Poll on Children's Health at the University of Michigan. A fourth of these parents say their child experiences occasional sleep problems (one to two nights per week) while 18 percent believe their teen struggles with sleep three or more nights per week.

Not being able to stay off electronics -- including social media and cell phones -- was the no.1 reason parents cited for sleep disturbance.

Other reasons included irregular sleep schedules due to homework or activities (43 percent), worries about school (31 percent), and concerns about social life (23 percent). Ten percent of parents say their teen's sleep problems are related to a health condition or medication, cited more often by parents of teens who experience frequent sleep problems.

The new report is based on responses from a nationally representative household survey that included responses from 1,018 parents with at least one child 13-18 years old.

"This poll suggests that sleep problems are common among teens and parents believe late-night use of electronics are a main contributor," says poll co-director Sarah Clark, M.P.H.

"Teens' hectic schedules and homework load, as well as anxiety about school performance and peer relationships, also are seen by parents as contributing to sleep problems."

Parents polled say they've encouraged their teen to try different strategies at home to help with sleep problems, including limiting caffeine in the evening (54 percent), turning off electronics and cell phones at bedtime (53 percent), having a snack before bed (44 percent), and natural or herbal remedies, such as melatonin (36 percent). A quarter of parents (28 percent) say their teen has tried some type of medication to address sleep problems.

Forty percent of parents of teens with frequent sleep problems, and 22 percent of parents of teens with occasional sleep problems, say they have talked to a doctor about sleep struggles. Parents who have consulted with doctors say the top recommendations from experts included turning off electronics and cell phones at bedtime (72 percent), adhering to a regular sleep schedule (64 percent), limiting caffeine (47 percent), and taking natural remedies (42 percent).

When doctors recommended medication for teens' sleep problems, it was twice as likely to be prescription sleep medication rather than over-the-counter sleep or "nighttime" medicine, parents recalled. Yet parents rated over-the-counter sleep medicine as safer for teens than prescription sleep medicine.

"Parents whose teens continue to have frequent sleep problems, despite following recommendations for healthy sleep hygiene, may want to talk with a health care provider, particularly when considering which type of medication to try," says Clark.

"Inadequate or disrupted sleep can have long-lasting health effects that go beyond moodiness and irritability for teens," Clark adds.

"Sleep-deprived teens may have difficulty concentrating in school and those who drive have an increased risk of auto accidents. Inadequate sleep has also been linked to health problems ranging from obesity to depression.

Climate Change Could Hit Point of No Return by 2035

London, Sep 1 (Prensa Latina) Earth could go through a point of no return by 2035 if governments do not act decisively when it comes to fighting climate change, warns a study published in the Earth System Dynamics magazine.

Scientists at the University of Oxford say it would be unlikely to limit global warming to below two degrees Celsius by 2100 and consider that the deadline to reduce it to 1.5 degrees has already passed, unless radical climate action is taken.

The researchers wanted to find the last possible year to start reducing greenhouse gas emissions before it is too late.

In this regard, the concept of point of no return has the advantage of containing useful temporary information to report about the urgency of taking climate measures, says Matthias Aengenheyster, the study's lead author.

Through the use of information on climate models, the team determined the deadline to initiate actions, in order to keep global warming likely (with a probability of 67 percent) below two degrees Celsius by 2100.

This depends on how fast humanity can reduce emissions with the use of more renewable energy.

According to experts, the point of no return has already been exceeded for the most modest climate action scenario, where the proportion of renewable resources increases by two percent each year.

However, they consider that the elimination of greenhouse gases from the atmosphere, through the use of negative emission technology, could give the Earth a little more time: between six and 10 years.

  • Published in World

Local Albahaca Herb for Health

The local Albahaca is a bush that can reach a meter high with many wide and aromatic leaves which are often used in the Italian cook and It has small flowers of lilac, white and read colors.

It is about medicinal plant, which is also locally known as Alhábega, Alfábega, Basílica and Hierba real. It is useful to make a homemade cure for cough and sort throat. Its scientific name is Ocimumbasilicum.

That plant usually gets the direct sunray and it can be planted in well-drained flowerpots which do not accumulate water, but it needs it could be watered regularly and planted in flowerpots and well-fertilized plots of lands. It does not usually stand excessive coldness or heat. It does not resist many related harvests; therefore, it is necessary to plant it again.

Its leaves have an intense green color with many medicinal and cooking properties and it has a smell that makes people to feel happy. These are some the reasons by which the Albahaca plant should not be absent from the ecological and urban garden.

Local Albahaca Herb for Health

It grows easily in courtyards and gardens and the treatment against cough, phlegm, wound-scar formation, stomach disorders, lack of appetite, gases, soar throat, tonsillitis, snore disorders while sleeping, as well as nauseas, colics, anxiety, migraine and the beat of insects, are among its properties.

Its properties include its antispasmodic, digestive, anti-bacteria, fungicidal, insecticide, astringent, cicatrizant, stimulating and inflammatory reactions.

The leaves and stalks of this plant are the parts used of it to season potato omelets, meat soups, fish, chickens, salads, stuffed dishes, as well as sauces, sweets and liquors.The Albahaca plant can be perfectly combined with dishes which include tomate, olive oil, lemon, read meats, pastry and cheeses.

It is plant for an annual harvest and it comes from India and it certainly combines well with many foods like the tomato, aromatic plants like oregano, garlic and onions.

That plant prefers the warm environments and it does not stad the extreme cold. Its ideal temperature ranges from 15 to 25 Centigrade graded and it requires a fertile and fresh soil, besides, it survives well in an illuminated environment. However, it tolerates a semi-shadow one.

Although its most fruitful sowing process takes place in seedbeds, it could also be carried out in soil or in a flowerpot by burying its seeds up to 2 centimeters deep.

Local Albahaca Herb for Health

The most proper time for it is from February to April in humid land, then it is convenient provide them a higher quantity of light after 15 days, approximately.

Its proximity to other plants will keep it far from insects and plagues, especially the tomatoes which are also favored by it because of it protect them from parasites and it increases their flavors. It is much better to plant the aforementioned plant in places sheltered from the wind, taking into account that its branches are easily broken when there is an intense wind.

It is convenient to prune them every two weeks to secure a strong plant and abundant foliage. It is much better to water the soil directly than its leaves, instead.

If we wanted it to grow much more, then it is convenient to take out its flowers, unless we wanted to collect its seeds. However, we could use its pruned leaves for a year period. The best occasion for collecting and preserving it is precisely, as we have seen up to here, before its flowering period. Once it was collected, it could be used by us.

Local Albahaca Herb for Health

To frozen it, it is the best way to preserve it to be used and it should be placed in small quantities in the freezer compartment. Once is collected, it is advisable to hung it up side down in a fresh place under a shadow. Once it was dried, it should be placed into a glassed container.

Another of its benefits is the fact about being a sedative as if it was consumed at night, then it would help enjoying a pleasant dream. It is also antiseptic and anti-inflammatory one, thus, being a proper allied to face influenza.

It regulates the nerve system and it is recommended in cases of stress. It is a good and natural painkiller, especially in feverish conditions or general weakness sensation. It is a very digestive plant that helps correcting the gastrointestinal disorders.

By Teresa Valenzuela

Drug could aid recovery after a heart attack

Drugs currently undergoing development to treat anemia could be repurposed to help prevent people with Type 2 diabetes from developing heart failure, according to new research funded by the British Heart Foundation (BHF) and Diabetes UK.

In the study, published in the Journal of the American College of Cardiology, researchers found that, after a heart attack, a protein called HIF acts to help heart cells survive.

In people with diabetes, fats accumulate within the heart muscle and stop the HIF protein from becoming active. This means that a person is more likely to suffer lasting heart muscle damage, and develop heart failure after a heart attack.

Researchers from the University of Oxford treated diabetic rats with a drug known to activate the HIF protein, and were able to encourage the heart to recover after a heart attack. Further work is needed to see whether the same process can be replicated in people.

However, these initial results suggest that several drugs known to activate HIF -- and currently undergoing phase III clinical trials to treat people with anemia -- could potentially be given to people with diabetes immediately after a heart attack in the future.

Nearly 3.7 million people in the UK have been diagnosed with diabetes, with 90% living with Type 2 diabetes. If people don't receive a swift diagnosis and the right care, it can put people at much higher risk of developing heart and circulatory disease. In the UK there are nearly 200,000 hospital visits each year due to heart attacks. It is estimated that nearly a fifth (18.6%) of people who have a heart attack in the UK, also have diabetes (1).

Dr Lisa Heather, a BHF research fellow at the University of Oxford who led the research, said: "After a heart attack, people with Type 2 diabetes are more likely to develop heart failure more quickly, but we have not fully understood the reasons why that is the case.

"What we have shown with this research is that the metabolism of people with Type 2 diabetes means they have higher levels of fatty acids in the heart. This prevents signals going to the heart protective protein telling it to 'kick-in' after a heart attack.

"But what is perhaps most exciting, is that existing drugs -- currently being trialled for people with blood disorders -- can reverse that effect and allow the protein to be activated after a heart attack.

"This opens the possibility that, in the near future, we could also use these drugs to help treat heart attacks in people with Type 2 diabetes."

Professor Jeremy Pearson, Associate Medical Director at the British Heart Foundation, which part-funded the research, said: "This research in rats has not only identified the mechanism that could explain why people with Type 2 diabetes to have poorer outcomes after a heart attack, but also a practical way this might be prevented.

"Further studies will be needed to confirm if we see the same benefits in humans. But if we can reactivate the body's own defence system we may be able to reduce the damage caused by a heart attack and improve people's quality of life."

Anna Morris, Assistant Director of Research Strategy and Partnerships at Diabetes UK, who part-funded the research, said: "It's vital that we find ways to reduce the harm caused by diabetes. It's still early days, but this research is helping us to understand how to improve recovery after a heart attack, and we're looking forward to seeing how this could help people with Type 2 diabetes in the future.

"For now, the best way to reduce your risk of a heart attack is to keep your blood glucose, blood pressure and blood fat at healthy levels, seek help to stop smoking, and by being active and eating a healthy, balanced diet."

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